At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

ORGANIZATION OVERVIEW:

At the Lilly Innovation Center in Cambridge, Massachusetts, we explore how next generation therapeutics, new technologies, data analytics and new care models can improve patient health and the healthcare system. Our team in Cambridge shares a real passion for challenging conventional wisdom and creating an environment that embraces creative, break-through concepts. The Center offers a start-up environment with large company support. It is located in the heart of Massachusetts’ exploding science and technology cluster and is within walking distance of some of the best academic and industry innovators in the world.
We are seeking a highly motivated associate scientist to join our Genetic Medicine team at Eli Lilly Seaport Innovation Center, MA. The successful candidate will possess a background in chemistry, protein science, or biochemistry, and is familiar with diverse chromatographic techniques and protein QC process. She/he will be responsible for protein purifications, characterization, and inventory maintenance, optimization of purification methods for protein-conjugates, independently or in collaboration with others.

BASIC QUALIFICATIONS:

• Bachelor or Master degree in chemistry, biochemistry, protein science, or related field.

ADDITIONAL SKILLS/PREFERENCES:

• 1+ years of laboratory work experience in organic, analytical, or protein chemistry preferred.
• Preferably has experience in biochemistry assays, protein purification and analysis.
• Proficiency in independently executing research tasks.
• High learning agility in the field of new scientific concepts and techniques.
• Pay attention to details, ability to identify issues and demonstrate problem-solving skills in day-to-day research work.
• Excellent communication, time management, and organizational skills
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• Perform gram scale protein purification and characterization, such as size-exclusion chromatography, endotoxin, SDS PAGE gel, and mass spectrometry.
• Conduct antibody redox reactions and desalting process to provide high quality proteins for bioconjugation.
• Optimize purification methods for antibody-conjugates with novel payloads (e.g. oligonucleotides, small molecules or peptide linkers) using diverse chromatographic techniques.
• Responsible for maintenance of purification instruments and sanitization of chromatographic columns by following SOP.
• Work productively and safely in the laboratory; and maintain good practice in writing experimental report in an electronic lab notebook.
• Managing protein inventory by working closely with internal teams or external organizations.
• Communicate experimental results with supervisor and at team/department meetings.