Senior Bioinformatician

at  Asklepios BioPharmaceutical

Asklepios BioPharmaceutical, Inc. (AskBio) is a leading, clinical-stage gene therapy company founded in 2001 based on the work of adeno-associated virus (AAV) gene therapy visionary and pioneer, Jude Samulski, PhD. Since that time, our commitment to developing life-saving medicines that can potentially cure genetic diseases has never wavered.
At AskBio, we’ve built a foundation of therapeutic programs, AAV manufacturing and a rich portfolio of patented technology. Our therapeutic focus includes neuromuscular, central nervous system, cardiovascular and metabolic diseases with clinical trials underway for Pompe disease, Parkinson’s disease, and congestive heart failure. Our gene therapy platform includes Pro10™, an industry-leading proprietary cell line manufacturing process, and an extensive AAV capsid and promoter library.
We became a wholly-owned, independently operated, subsidiary of Bayer AG in late 2020 as a cornerstone of its newly formed Cell & Gene Therapy (CGT) platform. Our global headquarters is in Research Triangle Park, NC. Additionally, we have significant operations in Philadelphia, PA, Columbus, OH, Scotland, France, and Spain.
Our vision: Pioneering science to create transformative molecular medicines.
Our mission: Lead innovative science and drive clinical outcomes to transform people’s lives.

Our principles:

• Advance innovative science by pushing boundaries.
• Bring transformative therapeutics to patients in need.
• Provide an environment for employees to reach their fullest potential.

Our values:

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.
• Cultivate Collaboration. Strive to be the best teammate, actively listen, openly communicate, and embrace diverse points of view.
• Embrace Responsibility. We are humbled by the enormity of our mission. We hold a relentless commitment to advance science and clinical outcomes for our patients, families, and caregivers.
• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.
• Act with Uncompromising Integrity. Be honest, transparent, and committed to doing what’s right in every situation. Make clear commitments and follow through.

We are currently hiring for a Senior Bioinformatician in our Edinburgh, UK office reporting into the Sr Director, Bioinformatics and Machine Learning. The successful candidate will analyse and interpret complex biological datasets using state-of-the-art bioinformatics tools and techniques.

Responsibilities

• Develop and implement novel computational methods and algorithms for the analysis of proprietary biological data
• Collaborate with cross-functional international teams to understand their data analysis needs and provide tailored bioinformatics solutions
• Contribute to the design and development of bioinformatics pipelines and workflows to streamline data processing and analysis
• Stay up-to-date with the latest advancements in bioinformatics, machine learning, and data science, and incorporate them into your work
• Mentor and provide guidance to junior bioinformaticians, fostering a culture of knowledge sharing and continuous learning
• Present findings and recommendations to stakeholders, including senior leadership, effectively communicating complex technical information.

Minimum Requirements

• Master’s Degree in bioinformatics, other numerate discipline, and 10+ years experience
• Strong Python programming skills
• Statistical analysis of DNA sequence and molecular datasets
• Effective communication of complex concepts and data to non-experts
• Profiling of omic data from public and proprietary sources, particularly NGS data.

• Familiarity with Unix-like systems

Preferred Skills & Abilities

• Doctorate in bioinformatics or related discipline and at least 5 years experience
• Demonstrated ability to develop novel computational methods
• Experience analysing and interpreting clinical data
• Knowledge of data analysis languages, such as R/ Matlab
• Experience with Docker or similar
• Familiarity with integrating multi-omics datasets
• Knowledge of workflow management systems such as snakemake/nextflow
• Knowledge of gene therapy
• Experience contributing to projects involving cross-disciplinary and global teams
• Experience with version control systems (e.g., Git) and collaborative development practices.

Asklepios BioPharmaceutical, Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race, color, religion, gender, sexual orientation, gender identity, national origin, age, disability, veteran status or any other protected status prohibited under Federal, State or local laws. All employment decisions are based on valid job‐related requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website, you may request a reasonable accommodation to express interest in a specific opening by calling us at (919) 561-6210 or sending us an email at
careers@askbio.com.
Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio, through any medium, will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio, no fee or payment of any kind will be paid to the agency

• Develop and implement novel computational methods and algorithms for the analysis of proprietary biological data
• Collaborate with cross-functional international teams to understand their data analysis needs and provide tailored bioinformatics solutions
• Contribute to the design and development of bioinformatics pipelines and workflows to streamline data processing and analysis
• Stay up-to-date with the latest advancements in bioinformatics, machine learning, and data science, and incorporate them into your work
• Mentor and provide guidance to junior bioinformaticians, fostering a culture of knowledge sharing and continuous learning
• Present findings and recommendations to stakeholders, including senior leadership, effectively communicating complex technical information